The Multimodal Imaging Group staff is involved in the management of INM's computer systems and to coordinate a variety of activities directed towards the enhancement of INM's medical imaging portfolio.

Services

• Management of INM's personal computer system and computer controlled devices of GMP compatible Radiochemistry Laboratories.
• Management of Medical Imaging Servers including 50 core cluster, file and authentication servers and a high capacity backup system.
• Management of INM's email, web services and INM-wide network administration.
• Management of INM's DICOM server expanded by DicomBBox automated image processing software system. 
• Management of hardware and software of MiniPET lab and Biological Research labs.

 Image Processing and Software Development Projects

 Multimodal Imaging Software Distribution

• Maintaining and developing MultiModal Imaging (M3I) software library system and applications (BrainCAD, BrainLOC, BrainMOD, BrainCON, Virtuose etc. ) and support the distributed software (BrainCAD, BrainLOC).
• Implementing and developing C++ and R based tools for graph theoretical analysis for population level neuroimaging projects.
• Developing software system of the DICOM Server Based Automated Image Processing Service (DicomBBox) including CT-MRI, SPECT/PET-MRI registration, T1 based spatial normalization and T1 based automated regional analysis for functional data (PET, SPECT, fMRI, Loreta) 
• Maintaining and developing controlling software of in-house developed radiochemistry synthesis systems.

 MiniPET/CT

• Improving image quality of MiniPET scanner using hexagonal and non regular gridding 2D and 3D image reconstruction algorithms.
• Improving image quality of MiniPET scanner using special statistical methods in event processing algorithms.
• Adapting PET-image reconstruction and correction software onto High Performance Computing system.
• Developing Rat Brain Atlas for MiniPET  projects.
• Developing whole body small animal image registration methods for registering MiniPET images and MRI images acquired by human 1.5T - 3T MRI. 
• Extending MiniPET scanner with an flat-panel based small animal CT scanner. 

 Clinical Studies

• Applying graph theoretical analysis in clinical studies using EEG registrations. Collaborators: Dept. of Neurology, Kenézy Hospital 
• Applying graph theoretical analysis in clinical studies using resting state, activation fMRI and diffusion MRI images.Collabprators: Department of Biomedical Laboratory and Imaging Science
• Developing a network simulator for methodological validation of graph theoretical algorithms.
• Developing new method for checking the accuracy of high precision pathological CT-MRI registration using huge (more then 1000 subject) archived data. Collabprators: Department of Biomedical Laboratory and Imaging Science
• Validating our FDG-PET supported virtual bronhoscopy method and software. Collabprators: Josa A. Hospital, Scanomed Ltd.
• Developig a surface based registration method for diagnostic and low-dose chest CT registration.
• Validating a landmark based registration method for fused visualization of endocardial maps and MRI/PET images. Collabprators: Institute of Diagnostic Imaging and Radiation Oncology of the Kaposvár University
• Adapting image registration, spatial normalization, volumetric analysis and graph theoretical analysis software to running on High Performance Computing.

Selected Publications

• Clemens B., Puskás S., Bessenyei M., Emri M., Spisák T., Koselák M., Hollódy K., Fogarasi A., Kondákór I., Füle K., Fekete I. EEG functional connectivity of the intrahemispheric cortico-cortical network of idiopathic generalized epilepsy. Epilepsy Res, 2011. 96:11-23 
• Jakab A., Molnar P., Emri M., Berényi E. Glioma grade assessment by using histogram analysis of diffusion tensor imaging-derived maps. Neuroradiology, 2011. 53:483-491 
• Kovács A., Toth L., Glavák C., Liposits C., Hadjiev J., Antal G., Emri M., Vandulek C., Répa I. Integrating functional MRI information into conventional 3D radiotherapy planning of CNS tumors. Is it worth it? J Neuro-oncol, 2011.
• Gyöngyösi M., Hemetsberger R., Wolbank S., Kaun C., Posa A., Márián T., Balkay L., Emri M., Galuska L., Mikecz P., Petrási Z., Charwat S., Hemetsberger H., Blanco J., Maurer G. Imaging the Migration of Therapeutically Delivered Cardiac Stem Cells. Jacc Cardiovasc Imaging, 2010. 3:772-775 
• Kis S.A., Emri M., Opposits G., Bükki T., Valastyán I., Hegyesi G., Imrek J., Kalinka G., Molnár J., Novák D., Végh J., Kerék A., Trón L., Balkay L. Comparison of Monte Carlo simulated and measured parameters of miniPET scanner. Nucl Instrum Meth A, 2007. 571:449-452 
• Emri M., Glaub T., Berecz R., Lengyel Z., Mikecz P., Répa I., Bartók E., Degrell I., Trón L. Brain blood flow changes measured by positron emission tomography during an auditory cognitive task in healthy volunteers and in schizophrenic patients. Prog Neuro-psychoph, 2006. 30:516-520
• Hegyesi G., Imrek J., Kalinka G., Molnár J., Novák D., Végh J., Balkay L., Emri M., Kis S.A., Molnár G., Trón L., Valastyán I., Bagaméry I., Bükki T., Rózsa S., Szabó Z., Kerék A. Ethernet based distributed data acquisition system for a small animal PET. Ieee T Nucl Sci, 2006. 53:2112-2117 
• Honbolygo F., Csepe V., Fekésházy A., Emri M., Márián T., Sárközy G. Converging evidences on language impairment in Landau-Kleffner Syndrome revealed by behavioral and brain activity measures: A case study. Clin Neurophysiol, 2006. 117:295-305
• Emri M., Kisely M., Lengyel Z., Balkay L., Márián T., Mikó L., Berényi E., Sziklai I., Trón L., Tóth Á. Cortical Projection of Peripheral Vestibular Signaling. J Neurophysiol, 2003. 89:2639-2646

Selected Posters

• Automated region analysis of brain PET examinations (EANM11)
• Region management toolkit for atlas-space image processing (ESMRMB11)
• Digital brain atlas assisted localization software for individual and population analysis of SPECT and PET data (EANM11)
• Registration of low-dose and diagnostic chest CT scans based on skeletal and bronchus surface models
• MultiModal Medical Imaging software and services for research and education

Selected Presentations 

• BrainLOC
• Virtual Bronchoscopy
• Agyatlaszok 

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